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Clinical Studies on Drug–Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Many drug–drug interactions (DDIs) are based on alterations of the plasma concentrations of a victim drug due to another drug causing inhibition and/or induction of the metabolism or transporter‐mediated disposition of the victim drug. In the worst case, such interactions cause more than tenfold inc...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacol Ther
Autori principali: Tornio, Aleksi, Filppula, Anne M., Niemi, Mikko, Backman, Janne T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563007/
https://ncbi.nlm.nih.gov/pubmed/30916389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1435
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