Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells

Breast cancer susceptibility gene 1 (BRCA1) is a tumor suppressor gene, which is frequently mutated in breast and ovarian cancers. BRCA1 plays a key role in the homologous recombination directed DNA repair, allowing its deficiency to act as a therapeutic target of DNA damaging agents. In this study,...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Acta Pharm Sin B
Hoofdauteurs: Zhang, Baoyuan, Lyu, Junfang, Yang, Eun Ju, Liu, Yifan, Wu, Changjie, Pardeshi, Lakhansing, Tan, Kaeling, Chen, Qiang, Xu, Xiaoling, Deng, Chu-Xia, Shim, Joong Sup
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Original article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161709/
https://ncbi.nlm.nih.gov/pubmed/32322466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.08.008
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items