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Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1(mut) lower grade gliomas

BACKGROUND: Early detection of increased aggressiveness of brain tumors is a major challenge in the field of neuro-oncology because of the inability of traditional imaging to uncover it. Isocitrate dehydrogenase (IDH)-mutant gliomas represent an ideal model system to study the molecular mechanisms a...

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書誌詳細
出版年:Neuro Oncol
主要な著者: Ruiz-Rodado, Victor, Malta, Tathiane M, Seki, Tomohiro, Lita, Adrian, Dowdy, Tyrone, Celiku, Orieta, Cavazos-Saldana, Alejandra, Li, Aiguo, Liu, Yang, Han, Sue, Zhang, Wei, Song, Hua, Davis, Dionne, Lee, Sunmin, Trepel, Jane B, Sabedot, Thais S, Munasinghe, Jeeva, Yang, Chunzhang, Herold-Mende, Christel, Gilbert, Mark R, Cherukuri, Murali Krishna, Noushmehr, Houtan, Larion, Mioara
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158660/
https://ncbi.nlm.nih.gov/pubmed/31665443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz207
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