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CBMT-42. LOSS OF PROMOTER METHYLATION IN GLYCOLYTIC GENES IS ASSOCIATED WITH AGGRESSIVENESS IN IDH1-MUTANT LOWER GRADE GLIOMAS

BACKGROUND: Identification of malignant progression is a major challenge in the field of Neuro-Oncology because of inability of traditional imaging methods to distinguish pseudo-progression from true progression. IDH1-mutant gliomas represent an ideal model system to study the molecular mechanisms a...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Larion, Mioara, Rodado, Victor Ruiz, Seki, Tomohiro, Malta, Tathiane, Lita, Adrian, Dowdy, Tyrone, Celiku, Orieta, Saldana, Alejandra Cavazos, Li, Aiguo, Zhang, Wei, Song, Hua, Davis, Dionne, Lee, Sunmin, Neckers, Jane, Munasinghe, Jeeva, Noushmehr, Houtan, Herold-Mende, Christel, Gilbert, Mark, Cherukuri, Murali Krishna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217205/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.161
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