CBMT-42. LOSS OF PROMOTER METHYLATION IN GLYCOLYTIC GENES IS ASSOCIATED WITH AGGRESSIVENESS IN IDH1-MUTANT LOWER GRADE GLIOMAS

BACKGROUND: Identification of malignant progression is a major challenge in the field of Neuro-Oncology because of inability of traditional imaging methods to distinguish pseudo-progression from true progression. IDH1-mutant gliomas represent an ideal model system to study the molecular mechanisms a...

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Pubblicato in:Neuro Oncol
Autori principali: Larion, Mioara, Rodado, Victor Ruiz, Seki, Tomohiro, Malta, Tathiane, Lita, Adrian, Dowdy, Tyrone, Celiku, Orieta, Saldana, Alejandra Cavazos, Li, Aiguo, Zhang, Wei, Song, Hua, Davis, Dionne, Lee, Sunmin, Neckers, Jane, Munasinghe, Jeeva, Noushmehr, Houtan, Herold-Mende, Christel, Gilbert, Mark, Cherukuri, Murali Krishna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217205/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.161
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