Effect of a Chikungunya Virus–Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

IMPORTANCE: Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus prevalent worldwide. There are currently no licensed vaccines or therapies. OBJECTIVE: To evaluate the safety and tolerability of an investigational CHIKV virus–like particle (VLP) vaccine in endemic regions. DESIGN, SETTING, AND P...

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Bibliografische gegevens
Gepubliceerd in:JAMA
Hoofdauteurs: Chen, Grace L., Coates, Emily E., Plummer, Sarah H., Carter, Cristina A., Berkowitz, Nina, Conan-Cibotti, Michelle, Cox, Josephine H., Beck, Allison, O’Callahan, Mark, Andrews, Charla, Gordon, Ingelise J., Larkin, Brenda, Lampley, Rebecca, Kaltovich, Florence, Gall, Jason, Carlton, Kevin, Mendy, Jason, Haney, Doug, May, Jeanine, Bray, Amy, Bailer, Robert T., Dowd, Kimberly A., Brockett, Brittanie, Gordon, David, Koup, Richard A., Schwartz, Richard, Mascola, John R., Graham, Barney S., Pierson, Theodore C., Donastorg, Yeycy, Rosario, Nicolas, Pape, Jean William, Hoen, Bruno, Cabié, André, Diaz, Clemente, Ledgerwood, Julie E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Medical Association 2020
Onderwerpen:
Original Investigation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156994/
https://ncbi.nlm.nih.gov/pubmed/32286643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.2477
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