Effect of a Chikungunya Virus–Like Particle Vaccine on Safety and Tolerability Outcomes: A Randomized Clinical Trial

IMPORTANCE: Chikungunya virus (CHIKV) is a mosquito-borne Alphavirus prevalent worldwide. There are currently no licensed vaccines or therapies. OBJECTIVE: To evaluate the safety and tolerability of an investigational CHIKV virus–like particle (VLP) vaccine in endemic regions. DESIGN, SETTING, AND P...

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發表在:JAMA
Main Authors: Chen, Grace L., Coates, Emily E., Plummer, Sarah H., Carter, Cristina A., Berkowitz, Nina, Conan-Cibotti, Michelle, Cox, Josephine H., Beck, Allison, O’Callahan, Mark, Andrews, Charla, Gordon, Ingelise J., Larkin, Brenda, Lampley, Rebecca, Kaltovich, Florence, Gall, Jason, Carlton, Kevin, Mendy, Jason, Haney, Doug, May, Jeanine, Bray, Amy, Bailer, Robert T., Dowd, Kimberly A., Brockett, Brittanie, Gordon, David, Koup, Richard A., Schwartz, Richard, Mascola, John R., Graham, Barney S., Pierson, Theodore C., Donastorg, Yeycy, Rosario, Nicolas, Pape, Jean William, Hoen, Bruno, Cabié, André, Diaz, Clemente, Ledgerwood, Julie E.
格式: Artigo
語言:Inglês
出版: American Medical Association 2020
主題:
Original Investigation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156994/
https://ncbi.nlm.nih.gov/pubmed/32286643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2020.2477
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