Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)

BACKGROUND: Phase 1 evaluation of the VRC HIV DNA and rAd5 vaccines delivered intramuscularly (IM) supported proceeding to a Phase 2 b efficacy study. Here we report comparison of the IM, subcutaneous (SC) and intradermal (ID) routes of administration. METHODS: Sixty subjects were randomized to 6 sc...

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Xehetasun bibliografikoak
Egile Nagusiak: Enama, Mary E., Ledgerwood, Julie E., Novik, Laura, Nason, Martha C., Gordon, Ingelise J., Holman, LaSonji, Bailer, Robert T., Roederer, Mario, Koup, Richard A., Mascola, John R., Nabel, Gary J., Graham, Barney S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951381/
https://ncbi.nlm.nih.gov/pubmed/24621858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091366
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