Phase I Randomized Clinical Trial of VRC DNA and rAd5 HIV-1 Vaccine Delivery by Intramuscular (IM), Subcutaneous (SC) and Intradermal (ID) Administration (VRC 011)

BACKGROUND: Phase 1 evaluation of the VRC HIV DNA and rAd5 vaccines delivered intramuscularly (IM) supported proceeding to a Phase 2 b efficacy study. Here we report comparison of the IM, subcutaneous (SC) and intradermal (ID) routes of administration. METHODS: Sixty subjects were randomized to 6 sc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Enama, Mary E., Ledgerwood, Julie E., Novik, Laura, Nason, Martha C., Gordon, Ingelise J., Holman, LaSonji, Bailer, Robert T., Roederer, Mario, Koup, Richard A., Mascola, John R., Nabel, Gary J., Graham, Barney S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951381/
https://ncbi.nlm.nih.gov/pubmed/24621858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091366
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