Shared Genetic Risk Factors Across Carbamazepine‐Induced Hypersensitivity Reactions

Carbamazepine (CBZ) causes life‐threating T‐cell‐mediated hypersensitivity reactions, including serious cutaneous adverse reactions (SCARs) and drug‐induced liver injury (CBZ‐DILI). In order to evaluate shared or phenotype‐specific genetic predisposing factors for CBZ hypersensitivity reactions, we...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Nicoletti, Paola, Barrett, Sarah, McEvoy, Laurence, Daly, Ann K., Aithal, Guruprasad, Lucena, M. Isabel, Andrade, Raul J., Wadelius, Mia, Hallberg, Pär, Stephens, Camilla, Bjornsson, Einar S., Friedmann, Peter, Kainu, Kati, Laitinen, Tarja, Marson, Anthony, Molokhia, Mariam, Phillips, Elizabeth, Pichler, Werner, Romano, Antonino, Shear, Neil, Sills, Graeme, Tanno, Luciana K., Swale, Ashley, Floratos, Aris, Shen, Yufeng, Nelson, Matthew R., Watkins, Paul B., Daly, Mark J., Morris, Andrew P., Alfirevic, Ana, Pirmohamed, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156285/
https://ncbi.nlm.nih.gov/pubmed/31066027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1493
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