The p-i Concept: Pharmacological Interaction of Drugs With Immune Receptors

Por Pichler, Werner J
Publicado em 2008

Mechanisms of Drug-Induced Allergy

Por Schnyder, Benno, Pichler, Werner J.
Publicado em 2009

Anaphylactoid Reactions to Radiopaque Contrast Dye–Reply–I

Por Schnyder, Benno, Pichler, Werner J.
Publicado em 2009

Sulfamethoxazole Induces a Switch Mechanism in T Cell Receptors Containing TCRVβ20-1, Altering pHLA Recognition

Por Watkins, Stephan, Pichler, Werner J.
Publicado em 2013

Activating interactions of sulfanilamides with T cell receptors*

Por Watkins, Stephan, Pichler, Werner J.
Publicado no Open J Immunol (2013)

T cell receptor variable β20-1 harbors a nucleotide binding pocket in the CDR2β loop

Por Watkins, Stephan, Pichler, Werner J.
Publicado no Open J Immunol (2013)

Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions

Por Gerber, Basil O., Pichler, Werner J.
Publicado em 2006

Ceftobiprole associated agranulocytosis after drug rash with eosinophilia and systemic symptoms induced by vancomycin and rifampicin

Por Wendland, Thomas, Daubner, Barbara, Pichler, Werner J
Publicado em 2011

Delayed drug hypersensitivity: models of T-cell stimulation

Por Adam, Jacqueline, Pichler, Werner J, Yerly, Daniel
Publicado em 2011

NSAID intolerance: it is not always what it seems

Por Petkovic, Tatjana Pecaric, Pichler, Werner J, Hausmann, Oliver
Publicado em 2014

The involvement of specific t cells in the pathogenesis of metamizole-induced agranulocytosis

Por Adam, Jacqueline, Bünter, Antonia, Pichler, Werner J, Wendland, Thomas
Publicado em 2014

Multiple Drug Hypersensitivity

Por Pichler, Werner J., Srinoulprasert, Yuttana, Yun, James, Hausmann, Oliver
Publicado no Int Arch Allergy Immunol (2017)

Drug-related relapses in drug reaction with eosinophilia and systemic symptoms (DRESS)

Por Jörg, Lukas, Helbling, Arthur, Yerly, Daniel, Pichler, Werner J.
Publicado no Clin Transl Allergy (2020)

T-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevance

Por Yun, James, Cai, Fenfen, Lee, Frederick J, Pichler, Werner J
Publicado no Asia Pac Allergy (2016)

Cytotoxic T Lymphocytes Derived from Patients with Chronic Hepatitis C Virus Infection Kill Bystander Cells via Fas-FasL Interaction

Por Gremion, Christel, Grabscheid, Benno, Wölk, Benno, Moradpour, Darius, Reichen, Jürg, Pichler, Werner, Cerny, Andreas
Publicado em 2004

Acute Liver Failure in a Patient Treated With Metamizole

Por Krisai, Philipp, Rudin, Deborah, Grünig, David, Scherer, Kathrin, Pichler, Werner, Terracciano, Luigi, Krähenbühl, Stephan
Publicado no Front Pharmacol (2019)

Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness

Por Jörg-Walther, Lukas, Schnyder, Benno, Helbling, Arthur, Helsing, Karin, Schüller, Alexandra, Wochner, Annette, Pichler, Werner
Publicado no Clin Case Rep (2015)

Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo

Por Naisbitt, Dean J, Gordon, S Fraser, Pirmohamed, Munir, Burkhart, Christoph, Cribb, Alistair E, Pichler, Werner J, Park, B Kevin
Publicado em 2001

Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells

Por Burkhart, Christoph, von Greyerz, Salome, Depta, Jan P H, Naisbitt, Dean J, Britschgi, Markus, Park, Kevin B, Pichler, Werner J
Publicado em 2001

Abacavir Induced T Cell Reactivity from Drug Naïve Individuals Shares Features of Allo-Immune Responses

Por Adam, Jacqueline, Wuillemin, Natascha, Watkins, Stephan, Jamin, Heidi, Eriksson, Klara K., Villiger, Peter, Fontana, Stefano, Pichler, Werner J., Yerly, Daniel
Publicado em 2014