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The p-i Concept: Pharmacological Interaction of Drugs With Immune Receptors
The immune response in drug hypersensitivity is normally explained by the hapten hypothesis. It postulates that drugs with a molecular weight of less than 1000 D are too small to cause an immune response per se. However, if a chemically reactive drug or drug metabolite binds covalently to a protein...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
World Allergy Organization
2008
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651037/ https://ncbi.nlm.nih.gov/pubmed/23282405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WOX.0b013e3181778282 |
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