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Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions
Drug-induced hypersensitivity reactions are instructive examples of immune reactions against low molecular weight compounds. Classically, such reactions have been explained by the hapten concept, according to which the small antigen covalently modifies an endogenous protein; recent studies show stro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751435/ https://ncbi.nlm.nih.gov/pubmed/16584124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080119 |
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