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Genomic Risk Factors Driving Immune-Mediated Delayed Drug Hypersensitivity Reactions
Adverse drug reactions (ADRs) remain associated with significant mortality. Delayed hypersensitivity reactions (DHRs) that occur greater than 6 h following drug administration are T-cell mediated with many severe DHRs now associated with human leukocyte antigen (HLA) risk alleles, opening pathways f...
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| Izdano u: | Front Genet |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085493/ https://ncbi.nlm.nih.gov/pubmed/33936169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.641905 |
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