HLA-A★3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

BACKGROUND: Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B★1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS–TE...

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Detalhes bibliográficos
Main Authors: McCormack, Mark, Alfirevic, Ana, Bourgeois, Stephane, Farrell, John J., Kasperavičiūtė, Dalia, Carrington, Mary, Sills, Graeme J., Marson, Tony, Jia, Xiaoming, de Bakker, Paul I.W., Chinthapalli, Krishna, Molokhia, Mariam, Johnson, Michael R., O’Connor, Gerard D., Chaila, Elijah, Alhusaini, Saud, Shianna, Kevin V., Radtke, Rodney A., Heinzen, Erin L., Walley, Nicole, Pandolfo, Massimo, Pichler, Werner, Park, B. Kevin, Depondt, Chantal, Sisodiya, Sanjay M., Goldstein, David B., Deloukas, Panos, Delanty, Norman, Cavalleri, Gianpiero L., Pirmohamed, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113609/
https://ncbi.nlm.nih.gov/pubmed/21428769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1013297
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