HLA-A★3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

BACKGROUND: Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B★1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens–Johnson syndrome and toxic epidermal necrolysis (SJS–TE...

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Autores principales: McCormack, Mark, Alfirevic, Ana, Bourgeois, Stephane, Farrell, John J., Kasperavičiūtė, Dalia, Carrington, Mary, Sills, Graeme J., Marson, Tony, Jia, Xiaoming, de Bakker, Paul I.W., Chinthapalli, Krishna, Molokhia, Mariam, Johnson, Michael R., O’Connor, Gerard D., Chaila, Elijah, Alhusaini, Saud, Shianna, Kevin V., Radtke, Rodney A., Heinzen, Erin L., Walley, Nicole, Pandolfo, Massimo, Pichler, Werner, Park, B. Kevin, Depondt, Chantal, Sisodiya, Sanjay M., Goldstein, David B., Deloukas, Panos, Delanty, Norman, Cavalleri, Gianpiero L., Pirmohamed, Munir
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113609/
https://ncbi.nlm.nih.gov/pubmed/21428769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1013297
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