Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

Phenytoin and carbamazepine are effective and inexpensive anti-epileptic drugs (AEDs). As with many AEDs, a broad range of doses is used, with the final “maintenance” dose normally determined by trial and error. Although many genes could influence response to these medicines, there are obvious candi...

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Detalhes bibliográficos
Main Authors: Tate, Sarah K., Depondt, Chantal, Sisodiya, Sanjay M., Cavalleri, Gianpiero L., Schorge, Stephanie, Soranzo, Nicole, Thom, Maria, Sen, Arjune, Shorvon, Simon D., Sander, Josemir W., Wood, Nicholas W., Goldstein, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556232/
https://ncbi.nlm.nih.gov/pubmed/15805193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407346102
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