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Vav1 and mutant K-Ras synergize in the early development of pancreatic ductal adenocarcinoma in mice
To explore the contribution of Vav1, a hematopoietic signal transducer, to pancreatic ductal adenocarcinoma (PDAC) development, we generated transgenic mouse lines expressing, Vav1, K-Ras(G12D), or both K-Ras(G12D) and Vav1 in pancreatic acinar cells. Co-expression of Vav1 and K-Ras(G12D) synergisti...
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| 出版年: | Life Sci Alliance |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Life Science Alliance LLC
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7156281/ https://ncbi.nlm.nih.gov/pubmed/32277014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000661 |
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