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Mechanism of protein cleavage at asparagine leading to protein-protein crosslinks

Long-lived proteins are present in numerous tissues within the human body. With age, they deteriorate, often leading to the formation of irreversible modifications such as peptide bond cleavage and covalent crosslinking. Currently understanding of the mechanism of formation of these crosslinks is li...

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Bibliografiske detaljer
Udgivet i:Biochem J
Main Authors: Friedrich, Michael G., Wang, Zhen, Schey, Kevin L., Truscott, Roger J. W.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156126/
https://ncbi.nlm.nih.gov/pubmed/31794011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190743
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