Large-Scale Binding of α-Crystallin to Cell Membranes of Aged Normal Human Lenses: A Phenomenon That Can Be Induced by Mild Thermal Stress

door Friedrich, Michael G., Truscott, Roger J. W.
Gepubliceerd in 2010

The etiology of human age-related cataract. Proteins don’t last forever

door Truscott, Roger J.W., Friedrich, Michael G.
Gepubliceerd in Biochim Biophys Acta (2015)

Can the Fact That Myelin Proteins Are Old and Break down Explain the Origin of Multiple Sclerosis in Some People?

door Truscott, Roger J. W., Friedrich, Michael G.
Gepubliceerd in J Clin Med (2018)

Molecular Processes Implicated in Human Age-Related Nuclear Cataract

door Truscott, Roger J. W., Friedrich, Michael G.
Gepubliceerd in Invest Ophthalmol Vis Sci (2019)

Degradation of an Old Human Protein: AGE-DEPENDENT CLEAVAGE OF γS-CRYSTALLIN GENERATES A PEPTIDE THAT BINDS TO CELL MEMBRANES

door Friedrich, Michael G., Lam, Jackson, Truscott, Roger J. W.
Gepubliceerd in 2012

Old Proteins in Man: a Field in its Infancy

door Truscott, Roger J.W., Schey, Kevin L., Friedrich, Michael G.
Gepubliceerd in Trends Biochem Sci (2016)

DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione

door Friedrich, Michael G., Wang, Zhen, Schey, Kevin L., Truscott, Roger J. W.
Gepubliceerd in Biochim Biophys Acta Gen Subj (2018)

Spontaneous cross-linking of proteins at aspartate and asparagine residues is mediated via a succinimide intermediate

door Friedrich, Michael G., Wang, Zhen, Schey, Kevin L., Truscott, Roger J. W.
Gepubliceerd in Biochem J (2018)

Mechanism of protein cleavage at asparagine leading to protein-protein crosslinks

door Friedrich, Michael G., Wang, Zhen, Schey, Kevin L., Truscott, Roger J. W.
Gepubliceerd in Biochem J (2019)

Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?

door Friedrich, Michael G., Hancock, Sarah E., Raftery, Mark J., Truscott, Roger J. W.
Gepubliceerd in Acta Neuropathol Commun (2016)

Hotspots of Age-Related Protein Degradation. The Importance of Neighbouring Residues for the Formation of Non-Disulfide Crosslinks derived from Cysteine

door Friedrich, Michael G., Wang, Zhen, Oakley, Aaron, Schey, Kevin L., Truscott, Roger J. W.
Gepubliceerd in Biochem J (2017)

Spatiotemporal Changes in the Human Lens Proteome: Critical Insights into Long-lived Proteins

door Schey, Kevin L., Wang, Zhen, Friedrich, Michael G., Garland, Donita L., Truscott, Roger J.W.
Gepubliceerd in Prog Retin Eye Res (2019)

The phospholipid composition of the human entorhinal cortex remains relatively stable over 80 years of adult aging

door Hancock, Sarah E., Friedrich, Michael G., Mitchell, Todd W., Truscott, Roger J. W., Else, Paul L.
Gepubliceerd in GeroScience (2017)

Understanding the α-crystallin cell membrane conjunction

door Su, Shih-Ping, McArthur, Jason D., Friedrich, Michael G., Truscott, Roger J.W., Aquilina, J. Andrew
Gepubliceerd in 2011

Tau Is Truncated in Five Regions of the Normal Adult Human Brain

door Friedrich, Michael G., Skora, Amanda, Hancock, Sarah E., Mitchell, Todd W., Else, Paul L., Truscott, Roger J. W.
Gepubliceerd in Int J Mol Sci (2021)

Sphingolipid distribution changes with age in the human lens

door Deeley, Jane M., Hankin, Joseph A., Friedrich, Michael G., Murphy, Robert C., Truscott, Roger J. W., Mitchell, Todd W., Blanksby, Stephen J.
Gepubliceerd in 2010

Tight binding of proteins to membranes from older human cells

door Truscott, Roger J. W., Comte-Walters, Susana, Ablonczy, Zsolt, Schwacke, John H., Berry, Yoke, Korlimbinis, Anastasia, Friedrich, Michael G., Schey, Kevin L.
Gepubliceerd in 2010

Is S-methylation in the human lens a result of non-enzymatic methylation by Sadenosylmethionine?

door Truscott, Roger J.W., Mizdrak, Jasminka, Friedrich, Michael G., Hooi, Michelle Y., Lyons, Brian, Jamie, Joanne F., Davies, Michael J., Wilmarth, Philip A., David, Larry L.
Gepubliceerd in 2012