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DehydroalanylGly, a new post translational modification resulting from the breakdown of glutathione

BACKGROUND: The human body contains numerous long-lived proteins which deteriorate with age, typically by racemisation, deamidation, crosslinking and truncation. Previously we elucidated one reaction responsible for age-related crosslinking, the spontaneous formation of dehydroalanine (DHA) intermed...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Gen Subj
Main Authors: Friedrich, Michael G., Wang, Zhen, Schey, Kevin L., Truscott, Roger J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7020663/
https://ncbi.nlm.nih.gov/pubmed/29309825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2018.01.003
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