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Regulating the Regulator: Post-Translational Modification of Ras
Ras proteins are monomeric GTPases that act as binary molecular switches to regulate a wide range of cellular processes. The exchange of GTP for GDP on Ras is regulated by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs), which regulate the activation state of Ras wit...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3879958/ https://ncbi.nlm.nih.gov/pubmed/22189424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3255 |
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