UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks

Chemical modifications and adducts at DNA double-strand break (DSB) ends must be cleaned before re-joining by non-homologous end-joining (NHEJ). MRE11 nuclease is essential for efficient removal of Topoisomerase II (TOP2)-DNA adducts from TOP2 poison-induced DSBs. However, mechanisms in MRE11 recrui...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:iScience
Main Authors: Akagawa, Remi, Trinh, Hai Thanh, Saha, Liton Kumar, Tsuda, Masataka, Hirota, Kouji, Yamada, Shintaro, Shibata, Atsushi, Kanemaki, Masato T., Nakada, Shinichiro, Takeda, Shunichi, Sasanuma, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155233/
https://ncbi.nlm.nih.gov/pubmed/32283528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101027
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados