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The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists
[Image: see text] Signal bias and membrane trafficking have recently emerged as important considerations in the therapeutic targeting of the glucagon-like peptide-1 receptor (GLP-1R) in type 2 diabetes and obesity. In the present study, we have evaluated a peptide series with varying sequence homolo...
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| Pubblicato in: | ACS Pharmacol Transl Sci |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2020
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7155199/ https://ncbi.nlm.nih.gov/pubmed/32296773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00022 |
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