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A Rational Design of a Biphasic Dissolution Setup—Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion

Biphasic dissolution systems achieved good predictability for the in vivo performance of several formulations of poorly water-soluble drugs by characterizing dissolution, precipitation, re-dissolution, and absorption. To achieve a high degree of predictive performance, acceptor media, aqueous phase...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceutics
Asıl Yazarlar: Denninger, Alexander, Westedt, Ulrich, Rosenberg, Jörg, Wagner, Karl G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150762/
https://ncbi.nlm.nih.gov/pubmed/32155962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12030237
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