A Miniaturized Extruder to Prototype Amorphous Solid Dispersions: Selection of Plasticizers for Hot Melt Extrusion

Hot-melt extrusion is an option to fabricate amorphous solid dispersions and to enhance oral bioavailability of poorly soluble compounds. The selection of suitable polymer carriers and processing aids determines the dissolution, homogeneity and stability performance of this solid dosage form. A mini...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmaceutics
मुख्य लेखकों: Lauer, Matthias E., Maurer, Reto, De Paepe, Anne T., Stillhart, Cordula, Jacob, Laurence, James, Rajesh, Kojima, Yuki, Rietmann, Rene, Kissling, Tom, van den Ende, Joost A., Schwarz, Sabine, Grassmann, Olaf, Page, Susanne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027370/
https://ncbi.nlm.nih.gov/pubmed/29783755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10020058
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