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Hot-Melt Extruded Amorphous Solid Dispersion for Solubility, Stability, and Bioavailability Enhancement of Telmisartan

Telmisartan (TEL, an antihypertensive drug) belongs to Class II of the Biopharmaceutical Classification System (BCS) because of its poor aqueous solubility. In this study, we enhanced the solubility, bioavailability, and stability of TEL through the fabrication of TEL-loaded pH-modulated solid dispe...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceuticals (Basel)
Asıl Yazarlar: Giri, Bhupendra Raj, Kwon, Jaewook, Vo, Anh Q., Bhagurkar, Ajinkya M., Bandari, Suresh, Kim, Dong Wuk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831136/
https://ncbi.nlm.nih.gov/pubmed/33477557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14010073
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