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Quality-by-design in hot melt extrusion based amorphous solid dispersions: An industrial perspective on product development

An industrially feasible approach to overcome the solubility and bioavailability limitations of poorly soluble active pharmaceutical ingredients is the development of amorphous solid dispersions (ASDs) using hot-melt extrusion (HME) technique. The application of Quality by Design (QbD) had a profoun...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Eur J Pharm Sci
Päätekijät: Butreddy, Arun, Bandari, Suresh, Repka, Michael A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855693/
https://ncbi.nlm.nih.gov/pubmed/33253883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2020.105655
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