The Development and Optimization of Hot-Melt Extruded Amorphous Solid Dispersions Containing Rivaroxaban in Combination with Polymers

Rivaroxaban (RXB), a novel oral anticoagulant that directly inhibits factor Xa, is a poorly soluble drug belonging to Biopharmaceutics Classification System (BCS) class II. In this study, a hot-melt extruded amorphous solid dispersion (HME-ASD) containing RXB is prepared by changing the drug:polymer...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Pharmaceutics
Hlavní autoři: Lee, Jong-Hwa, Jeong, Hyeong Sik, Jeong, Jong-Woo, Koo, Tae-Sung, Kim, Do-Kyun, Cho, Young Ho, Lee, Gye Won
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001048/
https://ncbi.nlm.nih.gov/pubmed/33800741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030344
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky