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Drug Permeation against Efflux by Two Transporters

The development of new antibiotics against Gram-negative bacteria is hampered by the powerful protective properties of their cell envelope. This envelope consists of two membranes augmented by efflux transporters, which act in synergy to restrict cellular access to a broad range of chemical compound...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Saha, Paramita, Sikdar, Samapan, Krishnamoorthy, Ganesh, Zgurskaya, Helen I., Rybenkov, Valentin V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150640/
https://ncbi.nlm.nih.gov/pubmed/32039579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00510
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