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Drug Permeation against Efflux by Two Transporters

The development of new antibiotics against Gram-negative bacteria is hampered by the powerful protective properties of their cell envelope. This envelope consists of two membranes augmented by efflux transporters, which act in synergy to restrict cellular access to a broad range of chemical compound...

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Dades bibliogràfiques
Publicat a:ACS Infect Dis
Autors principals: Saha, Paramita, Sikdar, Samapan, Krishnamoorthy, Ganesh, Zgurskaya, Helen I., Rybenkov, Valentin V.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7150640/
https://ncbi.nlm.nih.gov/pubmed/32039579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00510
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