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Interplay between Drug Efflux and Antioxidants in Escherichia coli Resistance to Antibiotics

We investigated possible cross talk between endogenous antioxidants glutathione, spermidine, and glutathionylspermidine and drug efflux in Escherichia coli. We found that cells lacking either spermidine or glutathione are less susceptible than the wild type to novobiocin and certain aminoglycosides....

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Bibliografske podrobnosti
Main Authors: Dhamdhere, Girija, Krishnamoorthy, Ganesh, Zgurskaya, Helen I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981227/
https://ncbi.nlm.nih.gov/pubmed/20876376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00719-10
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