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Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane
In Gram-negative bacteria, a synergistic relationship between slow passive uptake of antibiotics across the outer membrane and active efflux transporters creates a permeability barrier, which efficiently reduces the effective concentrations of antibiotics in cells and, hence, their activities. To an...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119019/ https://ncbi.nlm.nih.gov/pubmed/27697764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01882-16 |
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