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Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria

Gram-negative bacteria are notoriously resistant to antibiotics, but the extent of the resistance varies broadly between species. We report that in significant human pathogens Acinetobacter baumannii, Pseudomonas aeruginosa, and Burkholderia spp., the differences in antibiotic resistance are largely...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Krishnamoorthy, Ganesh, Leus, Inga V., Weeks, Jon W., Wolloscheck, David, Rybenkov, Valentin V., Zgurskaya, Helen I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666154/
https://ncbi.nlm.nih.gov/pubmed/29089426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01172-17
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