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Interplay between Drug Efflux and Antioxidants in Escherichia coli Resistance to Antibiotics

We investigated possible cross talk between endogenous antioxidants glutathione, spermidine, and glutathionylspermidine and drug efflux in Escherichia coli. We found that cells lacking either spermidine or glutathione are less susceptible than the wild type to novobiocin and certain aminoglycosides....

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Detalhes bibliográficos
Main Authors: Dhamdhere, Girija, Krishnamoorthy, Ganesh, Zgurskaya, Helen I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981227/
https://ncbi.nlm.nih.gov/pubmed/20876376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00719-10
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