KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function, KIR polymorphism associates with infectio...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Alicata, Claudia, Ashouri, Elham, Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Marin, Wesley M., Tao, Sudan, Moretta, Lorenzo, Hollenbach, Jill A., Trowsdale, John, Traherne, James A., Ghaderi, Abbas, Parham, Peter, Norman, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142237/
https://ncbi.nlm.nih.gov/pubmed/32300348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00556
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