KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

Natural killer (NK) cells are innate lymphocytes that eliminate infected and transformed cells. They discriminate healthy from diseased tissue through killer cell Ig-like receptor (KIR) recognition of HLA class I ligands. Directly impacting NK cell function, KIR polymorphism associates with infectio...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Alicata, Claudia, Ashouri, Elham, Nemat-Gorgani, Neda, Guethlein, Lisbeth A., Marin, Wesley M., Tao, Sudan, Moretta, Lorenzo, Hollenbach, Jill A., Trowsdale, John, Traherne, James A., Ghaderi, Abbas, Parham, Peter, Norman, Paul J.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7142237/
https://ncbi.nlm.nih.gov/pubmed/32300348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00556
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