SIRT1 Alleviates LPS-Induced IL-1β Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts

Emerging evidence indicates that aberrant maternal inflammation is associated with several pregnancy-related disorders such as preeclampsia, preterm birth, and intrauterine growth restriction. Sirtuin1 (SIRT1), a class III histone deacetylase, is involved in the regulation of various physiopathologi...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Park, Sumi, Shin, Jiha, Bae, Jeongyun, Han, Daewon, Park, Seok-Rae, Shin, Jongdae, Lee, Sung Ki, Park, Hwan-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140679/
https://ncbi.nlm.nih.gov/pubmed/32188057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030728
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