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Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1

BACKGROUND & AIMS: Tetrandrine (Tet) has been reported to have anti-inflammatory effects and protect from the ischemic strokes. The NLRP3 inflammasome plays a key role in cerebral ischemia/reperfusion (I/R)-induced inflammatory lesions. However, the molecular mechanisms of Tet related to the pro...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Wang, Jun, Guo, Ming, Ma, Ruojia, Wu, Maolin, Zhang, Yamei
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7211409/
https://ncbi.nlm.nih.gov/pubmed/32419986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9042
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