Pioglitazone ameliorates retinal ischemia/reperfusion injury via suppressing NLRP3 inflammasome activities

AIM: To explore the role of Pioglitazone (Pio) on a mouse model of retinal ischemia/reperfusion (I/R) injury and to elucidate the potential mechanism. METHODS: Retinal ischemia was induced in mice by increasing the intraocular pressure, and Pio was administered 4h though periocular injection before...

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Bibliografiske detaljer
Udgivet i:Int J Ophthalmol
Main Authors: Zhang, Yue-Lu, Wang, Ruo-Bing, Li, Wei-Yi, Xia, Fang-Zhou, Liu, Lin
Format: Artigo
Sprog:Inglês
Udgivet: International Journal of Ophthalmology Press 2017
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5733506/
https://ncbi.nlm.nih.gov/pubmed/29259897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2017.12.04
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