Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome

Shikonin (SHI) is an anti-inflammatory agent extracted from natural herbs. It is still unknown whether SHI ameliorates lipopolysaccharide (LPS)-induced cardiac dysfunction. This study aims to explore the protective effects of SHI on LPS-induced myocardial injury and its mechanism. The LPS-induced ca...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Physiol
Egile Nagusiak: Guo, Tao, Jiang, Zhong-Biao, Tong, Zhong-Yi, Zhou, Yang, Chai, Xiang-Ping, Xiao, Xian-Zhong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2020
Gaiak:
Physiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596688/
https://ncbi.nlm.nih.gov/pubmed/33178042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.570441
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