An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation

Mitochondria play an essential role in energy metabolism. Oxygen deprivation can poison cells and generate a chain reaction due to the free radical release. In patients with sepsis, the kidneys tend to be the organ primarily affected and the proximal renal tubules are highly susceptible to energy me...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Liu, Ruijin, Wang, Si-cong, Li, Ming, Ma, Xiao-hui, Jia, Xiao-nan, Bu, Yue, Sun, Lei, Yu, Kai-jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369665/
https://ncbi.nlm.nih.gov/pubmed/32733934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2398420
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