An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation

Mitochondria play an essential role in energy metabolism. Oxygen deprivation can poison cells and generate a chain reaction due to the free radical release. In patients with sepsis, the kidneys tend to be the organ primarily affected and the proximal renal tubules are highly susceptible to energy me...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Liu, Ruijin, Wang, Si-cong, Li, Ming, Ma, Xiao-hui, Jia, Xiao-nan, Bu, Yue, Sun, Lei, Yu, Kai-jiang
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369665/
https://ncbi.nlm.nih.gov/pubmed/32733934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2398420
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