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An Inhibitor of DRP1 (Mdivi-1) Alleviates LPS-Induced Septic AKI by Inhibiting NLRP3 Inflammasome Activation

Mitochondria play an essential role in energy metabolism. Oxygen deprivation can poison cells and generate a chain reaction due to the free radical release. In patients with sepsis, the kidneys tend to be the organ primarily affected and the proximal renal tubules are highly susceptible to energy me...

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Bibliografische gegevens
Gepubliceerd in:Biomed Res Int
Hoofdauteurs: Liu, Ruijin, Wang, Si-cong, Li, Ming, Ma, Xiao-hui, Jia, Xiao-nan, Bu, Yue, Sun, Lei, Yu, Kai-jiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369665/
https://ncbi.nlm.nih.gov/pubmed/32733934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2398420
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