CD3ε(+) Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS

Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes encoding proteins involved in the process of VDJ recombination retain partial activity and are classified as hypomorphs. Hypomorphic activity in the products from these genes can...

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Publicado en:Front Immunol
Autores principales: Boettcher, Adeline N., Cino-Ozuna, A. Giselle, Solanki, Yash, Wiarda, Jayne E., Putz, Ellie, Owens, Jeana L., Crane, Sara A., Ahrens, Amanda P., Loving, Crystal L., Cunnick, Joan. E., Rowland, Raymond R. R., Charley, Sara E., Dekkers, Jack C. M., Tuggle, Christopher K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136459/
https://ncbi.nlm.nih.gov/pubmed/32296428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00510
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