Novel Engraftment and T Cell Differentiation of Human Hematopoietic Cells in ART(−/−) IL2RG(−/Y) SCID Pigs

Pigs with severe combined immunodeficiency (SCID) are an emerging biomedical animal model. Swine are anatomically and physiologically more similar to humans than mice, making them an invaluable tool for preclinical regenerative medicine and cancer research. One essential step in further developing t...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Boettcher, Adeline N., Li, Yunsheng, Ahrens, Amanda P., Kiupel, Matti, Byrne, Kristen A., Loving, Crystal L., Cino-Ozuna, A. Giselle, Wiarda, Jayne E., Adur, Malavika, Schultz, Blythe, Swanson, Jack J., Snella, Elizabeth M., Ho, Chak-Sum (Sam), Charley, Sara E., Kiefer, Zoe E., Cunnick, Joan E., Putz, Ellie J., Dell'Anna, Giuseppe, Jens, Jackie, Sathe, Swanand, Goldman, Frederick, Westin, Erik R., Dekkers, Jack C. M., Ross, Jason W., Tuggle, Christopher K.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017803/
https://ncbi.nlm.nih.gov/pubmed/32117254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00100
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