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Development of Severe Combined Immunodeficient (SCID) Pig Models for Translational Cancer Modeling: Future Insights on How Humanized SCID Pigs Can Improve Preclinical Cancer Research

Within the last decade there have been several severe combined immunodeficient (SCID) pig models discovered or genetically engineered. The animals have mutations in ARTEMIS, IL2RG, or RAG1/2 genes, or combinations thereof, providing SCID pigs with NK cells, but deficient in T and B cells, or deficie...

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Asıl Yazarlar: Boettcher, Adeline N., Loving, Crystal L., Cunnick, Joan E., Tuggle, Christopher K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284365/
https://ncbi.nlm.nih.gov/pubmed/30560086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00559
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