CD3ε(+) Cells in Pigs With Severe Combined Immunodeficiency Due to Defects in ARTEMIS

Severe combined immunodeficiency (SCID) is described as the lack of functional T and B cells. In some cases, mutant genes encoding proteins involved in the process of VDJ recombination retain partial activity and are classified as hypomorphs. Hypomorphic activity in the products from these genes can...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Boettcher, Adeline N., Cino-Ozuna, A. Giselle, Solanki, Yash, Wiarda, Jayne E., Putz, Ellie, Owens, Jeana L., Crane, Sara A., Ahrens, Amanda P., Loving, Crystal L., Cunnick, Joan. E., Rowland, Raymond R. R., Charley, Sara E., Dekkers, Jack C. M., Tuggle, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7136459/
https://ncbi.nlm.nih.gov/pubmed/32296428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00510
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