Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress–induced senescence

Oxidative stress-induced DNA damage, the senescence-associated secretory phenotype (SASP), and impaired autophagy all are general features of senescent cells. However, the cross-talk among these events and processes is not fully understood. Here, using NIH3T3 cells exposed to hydrogen peroxide stres...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Han, Xiaojuan, Chen, Honghan, Gong, Hui, Tang, Xiaoqiang, Huang, Ning, Xu, Weitong, Tai, Haoran, Zhang, Gongchang, Zhao, Tingting, Gong, Chuhui, Wang, Shuang, Yang, Yu, Xiao, Hengyi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135980/
https://ncbi.nlm.nih.gov/pubmed/32047109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010734
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