Nrf2-SHP Cascade-Mediated STAT3 Inactivation Contributes to AMPK-Driven Protection Against Endotoxic Inflammation

Signal transducer and activator of transcription 3 (STAT3) is implicated in inflammation processing, but the mechanism of its regulation mostly remains limited to Janus kinase (JAK)-mediated phosphorylation. Although AMP-activated protein kinase (AMPK)-mediated STAT3 inactivation has got documented,...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Gong, Hui, Tai, Haoran, Huang, Ning, Xiao, Peng, Mo, Chunfen, Wang, Xiaobo, Han, Xiaojuan, Zhou, Jiao, Chen, Honghan, Tang, Xiaoqiang, Zhao, Tingting, Xu, Weitong, Gong, Chuhui, Zhang, Gongchang, Yang, Yu, Wang, Shuang, Xiao, Hengyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076194/
https://ncbi.nlm.nih.gov/pubmed/32210977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00414
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