AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD (+) elevation

AMPK activation is beneficial for cellular homeostasis and senescence prevention. However, the molecular events involved in AMPK activation are not well defined. In this study, we addressed the mechanism underlying the protective effect of AMPK on oxidative stress‐induced senescence. The results sho...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Han, Xiaojuan, Tai, Haoran, Wang, Xiaobo, Wang, Zhe, Zhou, Jiao, Wei, Xiawei, Ding, Yi, Gong, Hui, Mo, Chunfen, Zhang, Jie, Qin, Jianqiong, Ma, Yuanji, Huang, Ning, Xiang, Rong, Xiao, Hengyi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854918/
https://ncbi.nlm.nih.gov/pubmed/26890602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12446
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