AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD (+) elevation

AMPK activation is beneficial for cellular homeostasis and senescence prevention. However, the molecular events involved in AMPK activation are not well defined. In this study, we addressed the mechanism underlying the protective effect of AMPK on oxidative stress‐induced senescence. The results sho...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Han, Xiaojuan, Tai, Haoran, Wang, Xiaobo, Wang, Zhe, Zhou, Jiao, Wei, Xiawei, Ding, Yi, Gong, Hui, Mo, Chunfen, Zhang, Jie, Qin, Jianqiong, Ma, Yuanji, Huang, Ning, Xiang, Rong, Xiao, Hengyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854918/
https://ncbi.nlm.nih.gov/pubmed/26890602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12446
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