Restoring diabetes-induced autophagic flux arrest in ischemic/reperfused heart by ADIPOR (adiponectin receptor) activation involves both AMPK-dependent and AMPK-independent signaling

Macroautophagy/autophagy is increasingly recognized as an important regulator of myocardial ischemia-reperfusion (MI-R) injury. However, whether and how diabetes may alter autophagy in response to MI-R remains unknown. Deficiency of ADIPOQ, a cardioprotective molecule, markedly increases MI-R injury...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Wang, Yajing, Liang, Bin, Lau, Wayne Bond, Du, Yunhui, Guo, Rui, Yan, Zheyi, Gan, Lu, Yan, Wenjun, Zhao, Jianli, Gao, Erhe, Koch, Walter, Ma, Xin-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788496/
https://ncbi.nlm.nih.gov/pubmed/28825851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1358848
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