Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

Spns1 (Spinster homolog 1 [Drosophila]) in vertebrates, as well as Spin (Spinster) in Drosophila, is a hypothetical lysosomal H(+)-carbohydrate transporter, which functions at a late stage of macroautophagy (hereafter autophagy). The Spin/Spns1 defect induces aberrant autolysosome formation that lea...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Sasaki, Tomoyuki, Lian, Shanshan, Khan, Alam, Llop, Jesse R., Samuelson, Andrew V., Chen, Wenbiao, Klionsky, Daniel J., Kishi, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Basic Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324850/
https://ncbi.nlm.nih.gov/pubmed/27875093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1256934
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