Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain

The B cell adaptor protein (BCAP) is a multimodular regulator of inflammatory signaling in diverse immune system cells. BCAP couples TLR signaling to phosphoinositide metabolism and inhibits MyD88-directed signal transduction. BCAP is recruited to the TLR signalosome forming multitypic interactions...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Lauenstein, Johannes U., Scherm, Michael J., Udgata, Atul, Moncrieffe, Martin C., Fisher, David I., Gay, Nicholas J.
Format: Artigo
Langue:Inglês
Publié: AAI 2020
Sujets:
Molecular and Structural Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128310/
https://ncbi.nlm.nih.gov/pubmed/32198144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901210
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires