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Negative Regulation of TLR Signaling by BCAP Requires Dimerization of Its DBB Domain
The B cell adaptor protein (BCAP) is a multimodular regulator of inflammatory signaling in diverse immune system cells. BCAP couples TLR signaling to phosphoinositide metabolism and inhibits MyD88-directed signal transduction. BCAP is recruited to the TLR signalosome forming multitypic interactions...
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| 發表在: | J Immunol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
AAI
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7128310/ https://ncbi.nlm.nih.gov/pubmed/32198144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901210 |
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